Laybutt, D.R.: search on Z-Library

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1

On-target action of anti-tropomyosin drugs regulates glucose metabolism

Kee, Anthony J., Chagan, Jayshan, Chan, Jeng Yie, Bryce, Nicole S., Lucas, Christine A., Zeng, Jun, Hook, Jeff, Treutlein, Herbert, Laybutt, D. Ross, Stehn, Justine R., Gunning, Peter W., Hardeman, Ed

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 5.56 MB

english, 2018

2

Low serum PYY is linked to insulin resistance in first-degree relatives of subjects with type 2 diabetes

Dana Boey, Leonie Heilbronn, Amanda Sainsbury, Ross Laybutt, Adamandia Kriketos, Herbert Herzog, Lesley V. Campbell

Journal:

Year:

2006

Language:

english

File:

PDF, 495 KB

english, 2006

3

Inhibition of PKCɛ Improves Glucose-Stimulated Insulin Secretion and Reduces Insulin Clearance

Carsten Schmitz-Peiffer, D. Ross Laybutt, James G. Burchfield, Ebru Gurisik, Sakura Narasimhan, Christopher J. Mitchell, David J. Pedersen, Uschi Braun, Gregory J. Cooney, Michael Leitges, Trevor J. B

Journal:

Cell Metabolism

Year:

2007

Language:

english

File:

PDF, 834 KB

english, 2007

4

Muscle lipid availability and insulin resistance

E. W. Kraegen, N. D. Oakes, G. C. Cooney, D. R. Laybutt, K. S. Bell, C. Schmitz-peiffer, T. Biden, D. J. Chisholm

Year:

1997

Language:

english

File:

PDF, 29 KB

english, 1997

5

Induction of c-Myc Expression Suppresses Insulin Gene Transcription by Inhibiting NeuroD/BETA2-mediated Transcriptional Activation

Kaneto, H., Sharma, A., Suzuma, K., Laybutt, D. R., Xu, G., Bonner-Weir, S., Weir, G. C.

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 1.06 MB

english, 2002

6

Evidence against a role for NLRP3-driven islet inflammation in db/db mice

Kammoun, H.L., Allen, T.L., Henstridge, D.C., Barre, S., Coll, R.C., Lancaster, G.I., Cron, L., Reibe, S., Chan, J.Y., Bensellam, M., Laybutt, D.R., Butler, M.S., Robertson, A.A.B., O'Neill, L.A., Coo

Journal:

Molecular Metabolism

Year:

2018

Language:

english

File:

PDF, 1.03 MB

english, 2018

7

Muscle lipid accumulation and protein kinase C activation in the insulin-resistant chronically glucose-infused rat

Laybutt, D. Ross, Schmitz-Peiffer, Carsten, Saha, Asish K., Ruderman, Neil B., Biden, Trevor J., Kraegen, Edward W.

Journal:

American Journal of Physiology-Endocrinology and Metabolism

Year:

1999

Language:

english

File:

PDF, 160 KB

english, 1999

8

A fluorescent timer reporter enables sorting of insulin secretory granules by age

Yau, Belinda, Hays, Lori, Liang, Cassandra, Laybutt, David Ross, Thomas, Helen E, Gunton, Jenny E, Williams, Lindy, Hawthorne, Wayne J, Thorn, Peter, Rhodes, Christopher J., Kebede, Melkam A

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 2.94 MB

2020

9

Influence of diabetes on the loss of beta cell differentiation after islet transplantation in rats

D. R. Laybutt, Y. C. Hawkins, J. Lock, J. Lebet, A. Sharma, S. Bonner-Weir, G. C. Weir

Journal:

Year:

2007

Language:

english

File:

PDF, 303 KB

english, 2007

10

Pancreas-Specific Sirt1-Deficiency in Mice Compromises Beta-Cell Function without Development of Hyperglycemia

Pinho, Andreia V., Bensellam, Mohammed, Wauters, Elke, Rees, Maxine, Giry-Laterriere, Marc, Mawson, Amanda, Ly, Le Quan, Biankin, Andrew V., Wu, Jianmin, Laybutt, D. Ross, Rooman, Ilse, Itkin-Ansari,

Journal:

Year:

2015

Language:

english

File:

PDF, 3.05 MB

english, 2015

11

Reduced endoplasmic reticulum (ER)-to-Golgi protein trafficking contributes to ER stress in lipotoxic mouse beta cells by promoting protein overload

A. M. Preston, E. Gurisik, C. Bartley, D. R. Laybutt, T. J. Biden

Journal:

Year:

2009

Language:

english

File:

PDF, 194 KB

english, 2009

12

Potential role of the early response gene c-myc in beta-cell adaptation to changes in glucose concentration

Jonas, J., Laybutt, R., Steil, G. M., Trivedi, N., Weir, G. C., Henquin, J.

Journal:

Year:

2001

Language:

english

File:

PDF, 26 KB

english, 2001

13

β Cell Hypoxia-Inducible Factor-1α Is Required for the Prevention of Type 1 Diabetes

Lalwani, Amit, Warren, Joanna, Liuwantara, David, Hawthorne, Wayne J., O’Connell, Philip J., Gonzalez, Frank J., Stokes, Rebecca A., Chen, Jennifer, Laybutt, D. Ross, Craig, Maria E., Swarbrick, Micha

Journal:

Year:

2019

Language:

english

File:

PDF, 7.28 MB

english, 2019

14

Lipid-Induced Endoplasmic Reticulum Stress in Liver Cells Results in Two Distinct Outcomes: Adaptation with Enhanced Insulin Signaling or Insulin Resistance

Achard, Caroline S., Laybutt, D. Ross

Journal:

Year:

2012

Language:

english

File:

PDF, 734 KB

english, 2012

15

Genetic Regulation of Metabolic Pathways in -Cells Disrupted by Hyperglycemia

Laybutt, D. R., Sharma, A., Sgroi, D. C., Gaudet, J., Bonner-Weir, S., Weir, G. C.

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 498 KB

english, 2002

16

Structural constraints on the training of peer educators in hepatitis C prevention

Treloar, C., Rance, J., Laybutt, B., Crawford, S.

Journal:

Health Education Research

Year:

2012

Language:

english

File:

PDF, 104 KB

english, 2012

17

Inhibition of Id1 Augments Insulin Secretion and Protects Against High-Fat Diet-Induced Glucose Intolerance

Akerfeldt, M. C., Laybutt, D. R.

Journal:

Year:

2011

Language:

english

File:

PDF, 1006 KB

english, 2011

18

Beta-cell adaptation to hyperglycemia

Laybutt, R., Hasenkamp, W., Groff, A., Grey, S., Jonas, J., Kaneto, H., Sharma, A., Bonner-Weir, S., Weir, G.

Journal:

Year:

2001

Language:

english

File:

PDF, 32 KB

english, 2001

19

Differential regulation of adaptive and apoptotic unfolded protein response signalling by cytokine-induced nitric oxide production in mouse pancreatic beta cells

J. Y. Chan, G. J. Cooney, T. J. Biden, D. R. Laybutt

Journal:

Year:

2011

Language:

english

File:

PDF, 444 KB

english, 2011

20

Deletion of protein kinase Cδ in mice modulates stability of inflammatory genes and protects against cytokine-stimulated beta cell death in vitro and in vivo

J. Cantley, E. Boslem, D. R. Laybutt, D. V. Cordery, G. Pearson, L. Carpenter, M. Leitges, T. J. Biden

Journal:

Year:

2011

Language:

english

File:

PDF, 289 KB

english, 2011

21

Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring

Ng, Sheau-Fang, Lin, Ruby C. Y., Laybutt, D. Ross, Barres, Romain, Owens, Julie A., Morris, Margaret J.

Journal:

Year:

2010

Language:

english

File:

PDF, 205 KB

english, 2010

22

Downregulation of GLP-1 and GIP Receptor Expression by Hyperglycemia: Possible Contribution to Impaired Incretin Effects in Diabetes

Xu, G., Kaneto, H., Laybutt, D. R., Duvivier-Kali, V. F., Trivedi, N., Suzuma, K., King, G. L., Weir, G. C., Bonner-Weir, S.

Journal:

Year:

2007

Language:

english

File:

PDF, 787 KB

english, 2007

23

MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity

Jacovetti, Cécile, Abderrahmani, Amar, Parnaud, Géraldine, Jonas, Jean-Christophe, Peyot, Marie-Line, Cornu, Marion, Laybutt, Ross, Meugnier, Emmanuelle, Rome, Sophie, Thorens, Bernard, Prentki, Marc,

Journal:

Journal of Clinical Investigation

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

24

Malonyl CoA fuel sensing mechanism in muscle of insulin resistant rodents

N. B. Ruderman, A. K. Saha, D. Vavvas, T. Kurowski, D. R. Laybutt, E. W. Kraegen

Year:

1997

Language:

english

File:

PDF, 28 KB

english, 1997

25

Selective chronic regulation of GLUT1 and GLUT4 content by insulin, glucose, and lipid in rat cardiac muscle in vivo

Laybutt, D. R., Thompson, A. L., Cooney, G. J., Kraegen, E. W.

Journal:

American journal of physiology. Heart and circulatory physiology

Year:

1997

Language:

english

File:

PDF, 2.20 MB

english, 1997

26

Osteoglycin, a novel coordinator of bone and glucose homeostasis

Lee, N.J., Ali, N., Zhang, L., Qi, Y., Clarke, I., Enriquez, R.F., Brzozowska, M., Lee, I.C., Rogers, M.J., Laybutt, D.R., Center, J.R., Baldock, P.A., Herzog, H.

Journal:

Molecular Metabolism

Year:

2018

Language:

english

File:

PDF, 3.28 MB

english, 2018

27

Macrophage alterations in islets of obese mice linked to beta cell disruption in diabetes

Chan, Jeng Yie, Lee, Kailun, Maxwell, Emma L., Liang, Cassandra, Laybutt, D. Ross

Journal:

Year:

2019

Language:

english

File:

PDF, 1.13 MB

english, 2019

28

Pharmacological reduction of NEFA restores the efficacy of incretin-based therapies through GLP-1 receptor signalling in the beta cell in mouse models of diabetes

Z. F. Kang, Y. Deng, Y. Zhou, R. R. Fan, J. C. N. Chan, D. R. Laybutt…

Journal:

Year:

2013

Language:

english

File:

PDF, 670 KB

english, 2013

29

Glucose Transporter (GLUT-4) Is Targeted to Secretory Granules in Rat Atrial Cardiomyocytes

Jan W. Slot, Gabriella Garruti, Sally Martin, Viola Oorschot, George Posthuma, Edward W. Kraegen, Ross Laybutt, Gaétan Thibault and David E. James

Journal:

The Journal of Cell Biology

Year:

1997

Language:

english

File:

PDF, 5.40 MB

english, 1997

30

Overexpression of c-Myc in -Cells of Transgenic Mice Causes Proliferation and Apoptosis, Downregulation of Insulin Gene Expression, and Diabetes

Laybutt, D. R., Weir, G. C., Kaneto, H., Lebet, J., Palmiter, R. D., Sharma, A., Bonner-Weir, S.

Journal:

Year:

2002

Language:

english

File:

PDF, 1.47 MB

english, 2002

31

High Glucose Stimulates Early Response Gene c-Myc Expression in Rat Pancreatic Cells

Jonas, J.-C., Laybutt, D. R., Steil, G. M., Trivedi, N., Pertusa, J. G., Van de Casteele, M., Weir, G. C., Henquin, J.-C.

Journal:

Journal of Biological Chemistry

Year:

2001

Language:

english

File:

PDF, 244 KB

english, 2001

32

Hyper-activation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Upregulating the Proteostatic Machinery in Adipocytes

Minard, Annabel Y., Wong, Martin K. L., Chaudhuri, Rima, Tan, Shi-Xiong, Humphrey, Sean J., Parker, Benjamin L., Yang, Jean Y., Laybutt, D. Ross, Cooney, Gregory J., Coster, Adelle C. F., Stoeckli, Ja

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 1.72 MB

english, 2016

33

Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans

Bensellam, Mohammed, Shi, Yan-Chuan, Chan, Jeng Yie, Laybutt, D. Ross, Chae, Heeyoung, Abou-Samra, Michel, Pappas, Evan G., Thomas, Helen E., Gilon, Patrick, Jonas, Jean-Christophe

Journal:

Year:

2019

File:

PDF, 2.15 MB

2019

34

Translational Control Is Required for the Unfolded Protein Response and In Vivo Glucose Homeostasis

Donalyn Scheuner, Benbo Song, Edward McEwen, Chuan Liu, Ross Laybutt, Patrick Gillespie, Thom Saunders, Susan Bonner-Weir, Randal J Kaufman

Journal:

Year:

2001

Language:

english

File:

PDF, 696 KB

english, 2001

35

Alterations in MicroRNA Expression Contribute to Fatty Acid-Induced Pancreatic -Cell Dysfunction

Lovis, P., Roggli, E., Laybutt, D. R., Gattesco, S., Yang, J.-Y., Widmann, C., Abderrahmani, A., Regazzi, R.

Journal:

Year:

2008

Language:

english

File:

PDF, 377 KB

english, 2008

36

Influence of chronic hyperglycemia on the loss of the unfolded protein response in transplanted islets

Walters, S. N., Luzuriaga, J., Chan, J. Y., Grey, S. T., Laybutt, D. R.

Journal:

Journal of Molecular Endocrinology

Year:

2013

Language:

english

File:

PDF, 304 KB

english, 2013

37

Publisher Correction: Loss-of-function of the long non-coding RNA A830019P07Rik in mice does not affect insulin expression and secretion

Guay, Claudiane, Abdulkarim, Baroj, Tan, Jennifer Y., Dubuis, Gilles, RÃ¼tti, Sabine, Laybutt, David Ross, Widmann, Christian, Regazzi, Romano, Marques, Ana Claudia

Journal:

Scientific Reports

Year:

2020

File:

PDF, 638 KB

2020

38

Osteoglycin, a novel coordinator of bone and glucose homeostasis

Lee, Nicola J., Ali, N., Zhang, L., Qi, Y., Clarke, I., Enriquez, R.F., Brzozowska, M., Lee, I.C., Rogers, M.J., Laybutt, D.R., Center, J.R., Baldock, P.A., Herzog, Herbert

Journal:

Obesity Research & Clinical Practice

Year:

2019

File:

PDF, 284 KB

2019

39

Epidemics will always come (and go): the need to prepare for the next one, research on COVID-19, and the role of molecular and cellular endocrinology

Stratakis, Constantine A., Laybutt, D. Ross, Laudet, Vincent, Klinge, Carolyn M.

Journal:

Molecular and Cellular Endocrinology

Year:

2020

File:

PDF, 441 KB

2020

40

O50 Rôle de l’hypoxie et des facteurs de transcription HIF1 et HIF2 dans les altérations glucotoxiques de l’expression génique dans les cellules pancréatiques

M. Bensellam, Y. Guiot, D.R. Laybutt, J.C. Jonas

Journal:

Diabetes & Metabolism

Year:

2010

Language:

french

File:

PDF, 88 KB

french, 2010

41

Increased Expression of Antioxidant and Antiapoptotic Genes in Islets That May Contribute to -Cell Survival During Chronic Hyperglycemia

Laybutt, D. R., Kaneto, H., Hasenkamp, W., Grey, S., Jonas, J.-C., Sgroi, D. C., Groff, A., Ferran, C., Bonner-Weir, S., Sharma, A., Weir, G. C.

Journal:

Year:

2002

Language:

english

File:

PDF, 584 KB

english, 2002

42

p38 MAPK Is a Major Regulator of MafA Protein Stability under Oxidative Stress

Kondo, Takuma, Khattabi, Ilham El, Nishimura, Wataru, Laybutt, D. Ross, Geraldes, Pedro, Shah, Samit, King, George, Bonner-Weir, Susan, Weir, Gordon, Sharma, Arun

Journal:

Molecular Endocrinology

Year:

2009

Language:

english

File:

PDF, 298 KB

english, 2009

43

The molecular mechanisms of pancreatic β-cell glucotoxicity: Recent findings and future research directions

Bensellam, Mohammed, Laybutt, D. Ross, Jonas, Jean-Christophe

Journal:

Molecular and Cellular Endocrinology

Year:

2012

Language:

english

File:

PDF, 1.44 MB

english, 2012

44

Cross-talk between the unfolded protein response and nuclear factor-κB signalling pathways regulates cytokine-mediated beta cell death in MIN6 cells and isolated mouse islets

Chan, J. Y., Biden, T. J., Laybutt, D. R.

Journal:

Year:

2012

Language:

english

File:

PDF, 740 KB

english, 2012

45

Casitas b-Lineage Lymphoma-Deficient Mice Are Protected Against High-Fat Diet-Induced Obesity and Insulin Resistance

Molero, J. C., Waring, S. G., Cooper, A., Turner, N., Laybutt, R., Cooney, G. J., James, D. E.

Journal:

Year:

2006

Language:

english

File:

PDF, 312 KB

english, 2006

46

Failure of the Adaptive Unfolded Protein Response in Islets of Obese Mice Is Linked With Abnormalities in -Cell Gene Expression and Progression to Diabetes

Chan, J. Y., Luzuriaga, J., Bensellam, M., Biden, T. J., Laybutt, D. R.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.35 MB

english, 2013

47

NPY signalling in early osteoblasts controls glucose homeostasis

Lee, Nicola J., Nguyen, Amy D., Enriquez, Ronaldo F., Luzuriaga, Jude, Bensellam, Mohammed, Laybutt, Ross, Baldock, Paul A., Herzog, Herbert

Journal:

Molecular Metabolism

Year:

2015

Language:

english

File:

PDF, 2.41 MB

english, 2015

48

The balance between adaptive and apoptotic unfolded protein responses regulates β-cell death under ER stress conditions through XBP1, CHOP and JNK

Chan, Jeng Yie, Luzuriaga, Jude, Maxwell, Emma L., West, Phillip K., Bensellam, Mohammed, Laybutt, D. Ross

Journal:

Molecular and Cellular Endocrinology

Year:

2015

Language:

english

File:

PDF, 6.81 MB

english, 2015

49

Loss-of-function of the long non-coding RNA A830019P07Rik in mice does not affect insulin expression and secretion

Guay, Claudiane, Abdulkarim, Baroj, Tan, Jennifer Y., Dubuis, Gilles, RÃ¼tti, Sabine, Ross Laybutt, David, Widmann, Christian, Regazzi, Romano, Marques, Ana Claudia

Journal:

Scientific Reports

Year:

2020

File:

PDF, 1.17 MB

2020

50

Chronic Hyperglycemia, Independent of Plasma Lipid Levels, Is Sufficient for the Loss of -Cell Differentiation and Secretory Function in the db/db Mouse Model of Diabetes

Kjorholt, C., Akerfeldt, M. C., Biden, T. J., Laybutt, D. R.

Journal:

Year:

2005

Language:

english

File:

PDF, 184 KB

english, 2005

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